Andrographis paniculate extract (APE) has been used as a Thailand traditional medicine owing to andrographolide which is socksmith santa cruz effective for the viral clearance and prevention of disease progression.Several viral infections have been treated with APE, including SARS-CoV-2.The recommended dosage is 180 mg three times a royal nomadic 5413 rug day.We constructed a mathematical viral dynamic model of the SARS-CoV-2 model with andrographolide therapy by different doses.The pharmacokinetic/pharmacodynamic (PK/PD) model reduces the duration of viral clearance with a dose of 60 mg per day.
Moreover, APE improved the therapeutic efficacy of COVID-19 therapy.